Yeah, it did a li'l number on me too.
My periods weren't delayed, but they were a bit heavier, the smell was awful (I know, TMI), the cramps were relentless, & I bit everybody's head off (not the norm for me).
So no takey MSM for about a month now.
I may make some adjustments in intake amounts & increase water consumption w/it, but I consider myself on a break.