I've washed right after with no problems. I always used my own regular shampoo after using the neutralizer cuz I didn't like the smell. Back when I used to keep my blow dryer holstered at my hip, I always blow dried after relaxing. I'd deep condition with some cholesterol, slap in some blow dry lotion and go to it. Come to think of it, it always turned out silky, shiny and smooth. No wonder it took me so long to figure out the dryer was frying my ends lol.